A breakthrough therapy for polycythemia vera, a potentially fatal blood cancer, has emerged from a groundbreaking multi-center clinical trial led by the Icahn School of… Read More »Novel treatment holds promise to replace burdensome blood draws for polycythemia vera patients
Researchers and medical experts at Baylor College of Medicine are tackling the alarming rise of hepatoblastoma (HB), the most prevalent liver cancer among children. Over… Read More »HDAC inhibitor shows promise as part of new combination therapy for high-risk liver cancer in children
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes… Read More »New gene therapy technique uses bird retroelement for safe gene insertion
To prevent an emerging genomic technology from contributing to health disparities, a scientific team has devised new ways to improve a genetic testing method called… Read More »Recalibrated polygenic risk scores improve disease risk pediction in diverse populations
RNA polymerase is a key enzyme involved in the process of transcription, where genetic information encoded in DNA is transcribed into RNA molecules. This enzyme… Read More »RNA Polymerase
University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in… Read More »Novel plant protein fold identified for cyclic peptide formation in U-M study
A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health… Read More »Researchers develop new antibiotic effective against drug-resistant bacteria
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy… Read More »TYRP1-directed CAR T-cell therapy demonstrates efficacy in preclinical melanoma models
Researchers can engineer cells to express new genes and produce specific proteins, giving the cells new parts to work with. But, it’s much harder to… Read More »Researchers develop tool to orchestrate protein movement within cells
Penn Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for… Read More »New tool makes tiny protein clusters glow
When asked about what could cause cancer, people most likely think of chemicals like tobacco or radiation such as UV light in sunshine, but chronic… Read More »Chronic circadian disruption linked to liver cancer in humanized mice
Some immune cells in our bodies see their “killer instinct” restricted after entering solid tumors, according to new research. In a new paper published in… Read More »Gene editing corrects immune defect in mice and infants
Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing… Read More »CRISPR-Cas9 gene editing offers promise for children with rare immune disease
Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.… Read More »New protein target identified for aggressive pancreatic cancer
Researchers have grown tumors in the lab to accurately predict which drugs will work for people with bowel cancer—before they begin treatment. The world-first study… Read More »Tumor organoids accurately predict bowel cancer drug response
New research from Dartmouth College provides the first evidence that the Arctic’s frozen soil is the dominant force shaping Earth’s northernmost rivers. Permafrost, the thick… Read More »Permafrost holds back Arctic rivers, but thawing may unleash carbon flood
Researchers at The University of Texas at Austin, in collaboration with scientists from The University of Texas at Dallas and the University of Miami, are… Read More »Scientists uncover protein key to neuropathic pain
Just by looking at a short portion of a man’s genome it is possible to estimate the probability that he will die from prostate cancer—even… Read More »DNA test predicts prostate cancer mortality risk with 40% accuracy
Antibiotics have revolutionized the field of medicine, providing effective tools to combat bacterial infections and save countless lives. These powerful medications, derived from natural sources… Read More »Antibiotic
Protein synthesis inhibitors are a class of compounds that interfere with the processes involved in the synthesis of proteins within cells. These inhibitors can be… Read More »Protein synthesis inhibitor