New study finds microRNA-132 may protect against Alzheimer’s disease

A recent study conducted by the Netherlands Institute for Neuroscience and the VIB-KU Leuven Center for Brain and Disease Research has shed light on the potential impact of a tiny molecule known as microRNA-132 on various brain cells, suggesting its involvement in Alzheimer’s disease. RNA, similar to DNA, is composed of interconnected units and has … Read more

Universal donor stem cells could treat lethal brain conditions

Scientists at City of Hope have made a groundbreaking discovery by developing universal donor stem cells that could potentially revolutionize therapy for children with lethal brain conditions like Canavan disease, as well as individuals suffering from degenerative diseases such as Alzheimer’s and multiple sclerosis. The findings of this research study were recently published in Advanced … Read more

Swirling spiral brain signals reveal new insights into brain function

Scientists from the University of Sydney and Fudan University have made an intriguing discovery regarding human brain signals. They have found that these signals form swirling spirals across the outer layer of neural tissue, both during resting and cognitive states. The study, recently published in Nature Human Behaviour, suggests that these brain spirals play a … Read more

New folate-based radiopharmaceuticals could improve brain tumor detection

Folate-based radiopharmaceuticals have emerged as a promising tool for positron emission tomography (PET) imaging in the detection of folate receptors in brain tumors. This groundbreaking discovery, recently published in the esteemed journal Frontiers in Immunology, sheds new light on the potential exploitation of folate receptors in relation to brain tumors, particularly gliomas. Gliomas, a group … Read more

Japanese plum juice concentrate may reduce cardiovascular disease risk

High blood pressure, or hypertension, affects over 122 million Americans, accounting for approximately half of the population aged 20 and older. It is a significant contributor to cardiovascular disease, and despite advancements in treatment, individuals taking medications to manage their blood pressure still face a high risk of death from conditions like heart attack, heart … Read more

Venomous toadfish molecule shows promise in treating asthma

Researchers at the Butantan Institute in São Paulo, Brazil, have made an exciting discovery regarding a molecule found in the venom of the Thalassophryne nattereri, a venomous toadfish. In a recent study published in the journal Cells, scientists found that this molecule has the ability to control lung inflammation, making it a promising candidate for … Read more

New AI technique could revolutionize Alzheimer’s treatment

Researchers from the University of Rochester, led by Associate Professor Douglas Kelley, have developed a groundbreaking technique that utilizes artificial intelligence (AI) to measure fluid flow around the blood vessels of the brain. This innovative method has the potential to revolutionize the development of treatments for diseases like Alzheimer’s. The perivascular spaces surrounding cerebral blood … Read more

COVID-19 causes brain cells to fuse, leading to chronic neurological symptoms

Researchers at The University of Queensland have made a significant discovery regarding the effects of viruses such as SARS-CoV-2 on brain cells, leading to chronic neurological symptoms. Professor Massimo Hilliard and Dr. Ramon Martinez-Marmol from the Queensland Brain Institute conducted a study that examined how viruses can impact the nervous system. Their findings have been … Read more

Mutations in KEAP1-NRF2 pathway rewire metabolism and increase lysosomes in liver cancer

Researchers at Peter Mac, led by Dr. Andrew Cox and Dr. Kristin Brown, have made a significant breakthrough in understanding liver cancer development, as published in the Proceedings of the National Academy of Sciences (PNAS). Their study focused on the KEAP1-NRF2 pathway, known as a major driver pathway in cancer. By investigating the role of … Read more

Researchers find new target for treating neuropsychiatric disorders in adolescents

Scientists at the Del Monte Institute for Neuroscience at the University of Rochester have made significant progress in identifying a potential treatment target for neuropsychiatric disorders such as schizophrenia and autism. These conditions often emerge during early adulthood when the brain is still undergoing developmental changes. Dysfunction in the dopamine system, which plays a crucial … Read more

Parkinson’s drug ropinirole shows promise in slowing ALS progression, reveals early clinical trial

Researchers from Keio University School of Medicine in Tokyo have conducted an early clinical trial demonstrating the potential of the Parkinson’s disease drug ropinirole in treating amyotrophic lateral sclerosis (ALS). ALS, also known as Lou Gehrig’s disease, is a fatal motor neuron disease that leads to a progressive loss of muscle control. The trial, reported … Read more

Phage therapy gains public support as antibiotic resistance crisis worsens

A recent study published in PLOS ONE has found that the public is supportive of the development of bacteria-killing viruses as a potential alternative to antibiotics. The study also suggests that increased efforts to educate the public about this treatment can significantly increase their likelihood of using it. The rise of antimicrobial resistance (AMR) has … Read more

New machine-learning method reveals sex-specific genes and pathways in Alzheimer’s disease

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute have made a significant breakthrough in understanding Alzheimer’s disease (AD). They have developed a novel machine-learning method called Evolutionary Action Machine Learning (EAML) that enables the identification of sex-specific genes and molecular pathways associated with AD. The study, published in … Read more

Non-invasive brain imaging enables gesture recognition for brain-computer interfaces

A team of researchers from the University of California San Diego has made a significant breakthrough in the field of brain-computer interfaces. They have developed a method to distinguish hand gestures by analyzing data from noninvasive brain imaging alone, without any input from the hands themselves. This advancement has the potential to pave the way … Read more

Molecular mechanisms of memory development in youth

Our brains undergo a fascinating process in developing the ability to create specific memories. In a groundbreaking preclinical study conducted at The Hospital for Sick Children (SickKids), researchers have potentially uncovered a molecular cause for changes in memory during early childhood. When we talk about memories, we often refer to event-based memories or episodic memories. … Read more

Stanford medicine scientists discover how TMS reverses abnormal brain signals to treat depression

Scientists from Stanford Medicine have made a breakthrough in understanding how transcranial magnetic stimulation (TMS) relieves severe depression in patients who haven’t responded to standard treatments. Their research, published in the Proceedings of the National Academy of Sciences, reveals that TMS works by reversing abnormal brain signals, thereby altering the flow of neural activity in … Read more

Nourseothricin, a potential new treatment for multi-drug resistant bacterial infections

A recent study published in the open access journal PLOS Biology suggests that an old antibiotic could be a valuable weapon against multi-drug resistant bacterial infections. The research, conducted by James Kirby and colleagues from Harvard Medical School, highlights the potential of nourseothricin, a natural compound derived from a soil fungus. Nourseothricin was initially discovered … Read more