RNA polymerase is a key enzyme involved in the process of transcription, where genetic information encoded in DNA is transcribed into RNA molecules. This enzyme plays a crucial role in gene expression, as it catalyzes the synthesis of RNA strands complementary to a DNA template strand. Through its intricate structure and precise mechanism of action, … Read more
Amino acids are fundamental building blocks of proteins and play crucial roles in numerous biological processes. Understanding the structure, function, and significance of amino acids is essential for comprehending the complexity of living organisms and the molecular mechanisms that underlie their functions. Amino acids are organic molecules composed of a central carbon atom (referred to … Read more
DNA (Deoxyribonucleic Acid) and RNA (Ribonucleic Acid) are two fundamental molecules essential for life as we know it. While they share similarities in their chemical composition and play crucial roles in genetic processes, they also exhibit distinct differences that are essential for understanding the complexity of biological systems. DNA, famously known as the “molecule of … Read more
Cells lacking a nucleus and membrane-bound organelles are known as prokaryotic cells. These cells represent one of the two major categories of cells, the other being eukaryotic cells, which possess a nucleus and various membrane-bound organelles. Prokaryotic cells are found in two domains of life: Bacteria and Archaea. Despite their simplicity compared to eukaryotic cells, … Read more
When asked about what could cause cancer, people most likely think of chemicals like tobacco or radiation such as UV light in sunshine, but chronic jet lag probably does not come to mind. Human epidemiological studies have linked chronic jet lag, also known as chronic circadian dysfunction, to increased liver cancer risk. However, direct evidence … Read more
A study published in Science reports a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons at the mesoscopic level. The study was conducted by teams from the Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), the Institute of Neuroscience … Read more
Adenosine triphosphate, or ATP, serves as the primary energy currency in living organisms, playing a crucial role in various cellular processes across all forms of life. Its significance lies in its ability to store and transfer energy within cells, enabling fundamental biological functions necessary for life, growth, and reproduction. At its core, ATP consists of … Read more
An interdisciplinary collaboration has used a cutting-edge form of RNA tagging to map the gene expression that occurs during follicle maturation and ovulation in mice. The resulting atlas reveals a slew of previously unknown cellular and molecular interactions that drive ovulation, which is crucial for female fertility. The findings could prove pivotal for developing therapeutic … Read more
Ribosomes, often referred to as the cellular protein factories, are intricate molecular complexes that play a central role in the synthesis of proteins—a fundamental process crucial for the functioning and survival of all living organisms. These microscopic entities are essential components of cells, existing in both prokaryotic and eukaryotic organisms, and their discovery has paved … Read more
RNA (ribonucleic acid) and DNA (deoxyribonucleic acid) are both essential nucleic acids found in living cells, playing crucial roles in the storage and transmission of genetic information. Despite sharing some similarities, they exhibit key differences in terms of structure and function, reflecting their distinct roles within cellular processes. Structure At a fundamental level, both RNA … Read more
Neurotransmitters are essential signaling molecules in the nervous system, playing a central role in transmitting information between neurons and facilitating communication throughout the intricate neural networks. These chemical messengers enable the transmission of signals across synapses, the junctions between neurons, allowing for the precise and rapid communication necessary for various physiological processes. Understanding how neurotransmitters … Read more
The process of transcription is a fundamental molecular mechanism that plays a central role in the flow of genetic information within living cells. Transcription is the synthesis of RNA from a DNA template, and it is a crucial step in gene expression. This intricate process involves a series of molecular events that ensure the accurate … Read more
Researchers at Tulane University School of Medicine have devised a promising model for studying a pneumonia-causing fungus that has long eluded laboratory cultivation. Overcoming the challenge of growing Pneumocystis species outside a living lung, scientists utilized precision-cut lung tissue slices to investigate this fungus, a culprit behind Pneumocystis pneumonia in immunosuppressed patients and children. This … Read more
Molecular biology is a branch of biology that explores the structure, function, and interactions of molecules that make up the essential components of living organisms. It delves into the molecular mechanisms underlying various biological processes, including DNA replication, transcription, translation, and cellular signaling. At its core, molecular biology seeks to understand the molecular basis of … Read more
Biology is the scientific study of life and living organisms. It explores a vast range of topics, including the structure, function, growth, origin, evolution, and distribution of living organisms. This discipline delves into various levels of biological organization, from molecules and cells to organisms and ecosystems. Through methods like observation, experimentation, and analysis, biologists seek … Read more
Physiology, derived from the Greek words “physis” (nature) and “logos” (study), is the scientific discipline that explores the normal functioning of living organisms. It aims to understand the mechanisms that govern the various physiological processes within organisms, from the cellular level to complex organ systems. Physiology provides insights into how living organisms maintain homeostasis, respond … Read more
Bacillus subtilis is a gram-positive, rod-shaped bacterium that has garnered significant attention and application in various fields due to its versatility, resilience, and beneficial characteristics. This bacterium holds immense importance in both scientific research and industrial processes, playing a pivotal role in areas ranging from biotechnology to agriculture. First discovered in 1835 by Christian Gottfried … Read more
Today, medicines based on antibodies—proteins that fight infection and disease—are prescribed for everything from cancer to COVID-19 to high cholesterol. The antibody drugs are supplied by genetically-engineered cells that function as tiny protein-producing factories in the laboratory. Meanwhile, researchers have been targeting cancer, injuries to internal organs and a host of other ailments with new … Read more
Small nuclear RNA (snRNA) is a group of short RNA molecules found within the nucleus of eukaryotic cells. Despite their modest size, snRNAs play crucial roles in various aspects of gene expression, particularly in the processes of pre-mRNA splicing and gene regulation. This class of RNA molecules is part of a larger family of non-coding … Read more
The primary transcript is a crucial intermediate molecule in the process of gene expression, representing the initial RNA product synthesized from a DNA template during transcription. Understanding the formation and processing of primary transcripts is fundamental to unraveling the complexities of cellular biology, gene regulation, and the synthesis of functional RNA molecules. Transcription is the … Read more