TYRP1-directed CAR T-cell therapy demonstrates efficacy in preclinical melanoma models

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma. CAR T-cell therapy uses genetically engineered versions of a patient’s immune cells to target and destroy cancer cells. … Read more

Scientists reprogram canine stem cells from urine for painless therapies

In a significant stride towards veterinary regenerative treatment for dogs, scientists at Osaka Metropolitan University have devised a non-invasive and pain-free method to reprogram canine stem cells using urine samples. The findings, published in Stem Cell Reports, hold promise for advancing medical care for companion animals. Induced pluripotent stem cells (iPSCs) have been instrumental in … Read more

Biology

Biology is the scientific study of life and living organisms. It explores a vast range of topics, including the structure, function, growth, origin, evolution, and distribution of living organisms. This discipline delves into various levels of biological organization, from molecules and cells to organisms and ecosystems. Through methods like observation, experimentation, and analysis, biologists seek … Read more

What is medical science?

Medical science, also known as medicine, is a multidisciplinary field of study and practice that encompasses the understanding, diagnosis, treatment, and prevention of diseases and disorders affecting the human body. It integrates knowledge from various scientific disciplines, including biology, chemistry, physics, genetics, and psychology, to advance our understanding of health and illness. Medical science is … Read more

New study challenges assumptions about protein production in stem cells

Today, medicines based on antibodies—proteins that fight infection and disease—are prescribed for everything from cancer to COVID-19 to high cholesterol. The antibody drugs are supplied by genetically-engineered cells that function as tiny protein-producing factories in the laboratory. Meanwhile, researchers have been targeting cancer, injuries to internal organs and a host of other ailments with new … Read more

What is biotechnology?

Biotechnology is a multidisciplinary field that integrates biology, chemistry, genetics, and other scientific disciplines to harness biological systems and organisms for the development of useful products and technologies. It encompasses a wide range of applications, from healthcare and agriculture to industrial processes and environmental management. The core principle of biotechnology is the manipulation of living … Read more

Scientists uncover molecular steps leading to treatment-resistant prostate cancer

Researchers have achieved a groundbreaking milestone by meticulously documenting the molecular transformations that convert a common form of prostate cancer into a rare and treatment-resistant small cell neuroendocrine (SCN) cancer. This revelation opens new avenues for understanding tumor evolution, potentially leading to innovative therapies to impede the development of SCN prostate cancers. Dr. Owen Witte … Read more

What is an organoid?

Organoids are miniature, three-dimensional organ-like structures that are grown in vitro, replicating the architecture and functionality of real organs. These tiny structures hold immense potential in various fields, from biomedical research to drug discovery and personalized medicine. The term “organoid” is derived from the combination of “organ” and “oid,” meaning resembling or having the form … Read more

New technology offers hope for people with significant muscle damage

Evolved.Bio, a pioneering startup, brings a ray of hope to individuals grappling with significant muscle damage. Their groundbreaking technology enables the regeneration of muscle tissue with remarkable efficacy, offering a novel approach to in-vitro tissue creation. Unlike traditional methods involving foreign materials and cells, Evolved.Bio’s technique allows cells to recreate the components and structure of … Read more

How a tiny protein shapes the organ that sustains life

In a recent study suggests published in Circulation Research, researchers from the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Dr. José Luis de la Pompa, unveiled the crucial role played by the neuregulin-1 (Nrg1) protein in the intricate metamorphosis of the heart. This transformation, orchestrated by Nrg1, guides the heart’s journey from its delicate … Read more